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For research use only. Not FDA approved, not for human or veterinary use; data shown is published research, for educational reference.
Third-party tested 99%+ purity
Melanocortin Receptor Agonist

Melanotan II

121062-08-6

MT-II · Melanotan 2

Cyclic α-MSH analog for melanocortin-receptor pharmacology.

Mass
Price
$29.99$22.49
Quantity

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Release standard
99%+

Minimum purity by HPLC for every compound lot released.

Analyses per lot
2
Methods
HPLC · MS
Laboratory
Independent

Molecular profile

CAS number
121062-08-6
Molecular formula
C50H69N15O9
Molecular weight
1024.2 g/mol
Type
Cyclic heptapeptide, α-MSH analogue
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Catalogue number
ML10
Nominal mass
10 mg

Storage and handling

Appearance
Lyophilized powder
Solubility
Soluble in water
Storage
-20 °C, sealed and protected from light
Reconstituted
Refrigerate at 2-8 °C, use promptly
Classification
Laboratory research use only

Overview

Melanotan II is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH), designed with a lactam bridge that markedly increases its stability and receptor potency relative to the native hormone.

As a non-selective melanocortin-receptor agonist, Melanotan II is used in laboratory research on melanocortin pharmacology, including MC1R-mediated melanogenesis in pigment-cell models and comparative receptor-subtype binding studies across the melanocortin family.

Each vial contains 10 mg of lyophilized Melanotan II, sealed for laboratory use. This material is supplied strictly for in-vitro research and laboratory experimentation and is not for human or veterinary use of any kind.

Documented research areas

  • Melanocortin-receptor subtype binding and selectivity studies
  • Melanogenesis pathways in pigment-cell models
  • Cyclic-peptide stability and structure-activity research
  • Receptor-signaling assays (cAMP and downstream pathways)
Certificate of analysis

Available on request

Each lot is released against an HPLC purity result and a mass-spectrometry identity confirmation. Tested by an independent laboratory in Los Angeles, CA. Send us your lot number and we'll email that lot's report.

Catalog
ML10
Release standard
≥ 99% purity
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Usually sent the same business day.

Peer-reviewed literature

Selected published research on this compound

Independent, peer-reviewed work describing laboratory and clinical study of this compound. Listed so the research context on this page can be read at the source rather than taken on our word. These are not claims about this product.

  1. 01

    Life Sciences 1996

    Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide, in a pilot phase-I clinical study

    Dorr RT, Lines R, Levine N, et al.

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