Semax

Name: Semax
SKU: XA10
Price: 29.99 USD
Availability: InStock

80714-61-0

ACTH(4-7)-PGP · Met-Glu-His-Phe-Pro-Gly-Pro

ACTH-fragment heptapeptide used in neurotrophic-signaling research.

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Release standard

99%+

Minimum purity by HPLC for every compound lot released.

Analyses per lot: 2
Methods: HPLC · MS
Laboratory: Independent

Molecular profile

CAS number: 80714-61-0
Molecular formula: C₃₇H₅₁N₉O₁₀S
Molecular weight: 813.93 g/mol
Type: Heptapeptide, ACTH(4-7) analogue
Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Catalogue number: XA10
Nominal mass: 10 mg

Storage and handling

Appearance: Lyophilized powder
Solubility: Soluble in water
Storage: -20 °C, sealed and protected from light
Reconstituted: Refrigerate at 2-8 °C, use promptly
Classification: Laboratory research use only

Overview

Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) built from a fragment of adrenocorticotropic hormone, ACTH(4–7), extended with a Pro-Gly-Pro stabilizing sequence that protects it from rapid enzymatic breakdown.

In the laboratory, Semax is used in neuroscience research examining neurotrophic factor expression, particularly brain-derived neurotrophic factor (BDNF), along with melanocortin-receptor signaling in neural tissue and neuroprotection in cellular stress models.

Each vial contains 10 mg of lyophilized Semax, sealed for laboratory use. This material is supplied strictly for in-vitro research and laboratory experimentation and is not for human or veterinary use of any kind.

Documented research areas

BDNF and neurotrophic-factor expression studies
Melanocortin-receptor signaling in neural models
Neuroprotection assays under oxidative or ischemic stress
Cognitive-neuroscience and synaptic-plasticity research

Certificate of analysis

Available on request

Each lot is released against an HPLC purity result and a mass-spectrometry identity confirmation. Tested by an independent laboratory in Los Angeles, CA. Send us your lot number and we'll email that lot's report.

Catalog: XA10
Release standard: ≥ 99% purity

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Peer-reviewed literature

Selected published research on this compound

Independent, peer-reviewed work describing laboratory and clinical study of this compound. Listed so the research context on this page can be read at the source rather than taken on our word. These are not claims about this product.

01

Molecular Genetics and Genomics 2017

Semax, an analog of ACTH(4-7), regulates expression of immune response genes during ischemic brain injury in rats

Medvedeva EV, et al.